It functions as a conditional system capable of relatively rapid responses to a variety of stimuli
Vincent Jacob A, Wieczerzak Krystyna B, Gabriel Hanna M, Nardelli P, Rich Mark M, Cope Timothy C (2016) A novel path to chronic proprioceptive disability with oxaliplatin: distortion of sensory encoding
Moreover, the COVID-19 pandemic illustrates its substantial impact on long-term socioeconomic well-being due to the widespread and long-lasting consequences of efforts of pathogen containment 8 and the potential occurrence of post-acute sequelae such as long COVID 9
While originally isolated for its ability to promote slow-wave (deep) sleep, subsequent research has revealed DSIPs potential in influencing multiple physiological systems, including neuroprotection, hormone regulation, and pain modulation
"Increased Concentrations of Homocysteine in the Cerebrospinal Fluid in Patients with Fibromyalgia and Chronic Fatigue Syndrome"
The gut flora and MDD have been associated in most clinical studies and experimental data about the microbiomes involvement in the disorder